Article
Increased expression of highly branched N-glycans at cell surface is correlated with the malignant phenotypes of mouse tumor cells.
Cancer research - 15 Mar 1997
Asada M, Furukawa K, Segawa K, Endo T, Kobata A
Abstract excerpt
Three NIH3T3 transformants, MTAg, MTPy, and MT1, which grow similarly in soft agar media, showed remarkable differences in athymic mice: MTAg grew more rapidly than MTPy, whereas MT1 and NIH3T3 did not, and only MTAg metastasized in lung. Structural analysis of N-glycans from plasma membrane glyc...
Topics
- 3T3 Cells
- Animals
- Carbohydrate Sequence
- Cell Transformation, Neoplastic
- Glycosylation
- Lectins
- Lung Neoplasms
- Membrane Glycoproteins
- Mice
- Molecular Sequence Data
- Molecular Weight
- Neoplasm Proteins
- Neoplasm Transplantation
- Neoplasms, Experimental
- Phenotype
- Plant Lectins
- Polysaccharides
- Protein Processing, Post-Translational