Article
Relationship between metastasis-associated phenotypes and N-glycan structure of surface glycoproteins in human hepatocarcinoma cells.
Journal of cancer research and clinical oncology - 1 Apr 2001
Guo H B, Zhang Y, Chen H L
Abstract excerpt
PURPOSE: To study the relation of N-glycan structure on cell surface glycoproteins to the metastatic phenotypes. METHODS: Two human hepatocarcinoma 7721 cell lines transfected with sense or antisense cDNA of GnT-V, named GnT-V/7721 and GnT-V-AS/7721, respectively, were adopted, because GnT-V can change the antennary number and the content of the beta 1,6 GlcNAc branch in N-glycans. The effects of over- and...
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