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Article

Exogenous incorporation of neugc-rich mucin augments n-glycolyl sialic acid content and promotes malignant phenotype in mouse tumor cell lines.

Journal of experimental & clinical cancer research : CR - 1 Dec 2009

Gabri Mariano R, Otero Laura L, Gomez Daniel E, Alonso Daniel F

Abstract excerpt

BACKGROUND: Carbohydrates embedded in the plasma membrane are one of the main actors involved in the communication of cells with the microenvironment. Neuraminic sialic acids are glycocalyx sugars that play important roles in the modulation of malignant cell behaviour. N-glycolylneuraminic acid (NeuGc) is synthesized by the cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH), an enzyme expressed in...

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Source

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Identifiers

PMID: 19951433
DOI: 10.1186/1756-9966-28-146
PMCID: PMC2795750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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