Article
Delta sequence of Ty1 transposon can initiate transcription of the distal part of the URA2 gene complex in Saccharomyces cerevisiae.
FEMS microbiology letters - 1 Mar 1997
Roelants F, Potier S, Souciet J L, de Montigny J
Abstract excerpt
Expression of a silent aspartate transcarbamylase (ATCase) domain can occur by insertion of a Tyl retrotransposon within the coding sequence of a mutated ura2 allele. This unusual type of Ty-mediated gene activation is possible as the URA2 gene product is a multifunctional protein containing the...
Topics
- Alleles
- Aspartate Carbamoyltransferase
- DNA Transposable Elements
- Dihydroorotase
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Open Reading Frames
- Polymerase Chain Reaction
- Saccharomyces cerevisiae
- Transcription, Genetic
- Transcriptional Activation