Article
Severe adenine starvation activates Ty1 transcription and retrotransposition in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Sept 2005
Todeschini Anne-Laure, Morillon Antonin, Springer Mathias, Lesage Pascale
Abstract excerpt
Ty1 retrotransposons of the yeast Saccharomyces cerevisiae are activated by different kinds of stress. Here we show that Ty1 transcription is stimulated under severe adenine starvation conditions. The Bas1 transcriptional activator, responsible for the induction of genes of the de novo AMP biosynthesis pathway (ADE) in the absence of adenine, is not involved in this response. Activation occurs mainly on Ty1...
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