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Article

The central PPT of the yeast retrotransposon Ty1 is not essential for transposition.

Journal of molecular biology - 8 Aug 2003

Heyman T, Wilhelm M, Wilhelm F-X

Abstract excerpt

The yeast retrotransposon Ty1 has structural and functional similarities to retroviruses. We report here that, as in retroviruses, the plus-strand DNA of Ty1 is synthesized as two segments. A central DNA flap is formed during reverse transcription consecutive to elongation (with strand displacement) of the upstream segment beyond the central polypurine tract (cPPT) until the replication machinery is stopped at...

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PMID: 12888340
DOI: 10.1016/s0022-2836(03)00812-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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