Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Oct 1999

Bartels D J, Mitchell D A, Dong X, Deschenes R J

Abstract excerpt

Plasma membrane localization of Ras requires posttranslational addition of farnesyl and palmitoyl lipid moieties to a C-terminal CaaX motif (C is cysteine, a is any aliphatic residue, X is the carboxy terminal residue). To better understand the relationship between posttranslational processing and the subcellular localization of Ras, a yeast genetic screen was undertaken based on the loss of function of a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyltransferases
Share to Cell Compartmentation
Share to GTP-Binding Protein alpha Subunits

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heat-Shock Response

Share to Heterotrimeric GTP-Binding Proteins

Share to Palmitic Acid

Share to Protein Processing, Post-Translational

Share to ras Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 10490616
DOI: 10.1128/MCB.19.10.6775
PMCID: PMC84674

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae.PMID 10490616Read ↗

Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins.Semantic proximity Read ↗

Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae.Semantic proximity Read ↗

Regulation of Ras localization and cell transformation by evolutionarily conserved palmitoyltransferases.Semantic proximity Read ↗

Transmembrane topology of the protein palmitoyl transferase Akr1.Semantic proximity Read ↗

Mutations in the SHR5 gene of Saccharomyces cerevisiae suppress Ras function and block membrane attachment and palmitoylation of Ras proteins.Semantic proximity Read ↗

Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway.Semantic proximity Read ↗

Phenotypic effects of membrane protein overexpression in Saccharomyces cerevisiae.Semantic proximity Read ↗

Global analysis of protein palmitoylation in yeast.Semantic proximity Read ↗

Plasma membrane localization of Ras requires class C Vps proteins and functional mitochondria in Saccharomyces cerevisiae.Semantic proximity Read ↗

Plasma membrane localization is required for RasA-mediated polarized morphogenesis and virulence of Aspergillus fumigatus.Semantic proximity Read ↗

Functional analysis of Arabidopsis postprenylation CaaX processing enzymes and their function in subcellular protein targeting.Semantic proximity Read ↗

Modulation of Ras and a-factor function by carboxyl-terminal proteolysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.