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Article

p53 activates Fanconi anemia group C gene expression.

Human molecular genetics - 1 Feb 1997

Liebetrau W, Budde A, Savoia A, Grummt F, Hoehn H

Abstract excerpt

The tumor suppressor protein p53 (wtp53) can bind to specific target sequences and activate transcription of genes adjacent to these DNA elements. Two p53 binding sites are present in the gene coding for the Fanconi anemia complementation group C (FAC), one in the promoter region (from -1295 to -1266) and one in the coding region of FAC (from +1828 to +1848). Gel shift experiments show that wtp53 binds to the p53...

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Share to Binding Sites
Share to DNA-Binding Proteins
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Nuclear Proteins

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 9063748
DOI: 10.1093/hmg/6.2.277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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