Article
Mutations in a hydrophilic part of the core gene of hepatitis C virus in patients with hepatocellular carcinoma in China.
Journal of gastroenterology - 1 Feb 1997
Shimizu I, Yao D F, Horie C, Yasuda M, Shiba M, Horie T, Nishikado T, Meng X Y, Ito S
Abstract excerpt
We investigated the association between hepatocellular carcinoma (HCC) and the genomic characteristics of the hepatitis C virus (HCV) isolated from residents of the inshore region of the Yangtze River, an area that has one of the highest incidence of HCC in China. We determined the genomic heterogeneity of HCV, and the sequence divergence of the HCV core gene in individuals with chronic hepatitis and HCC. HCV...
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