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Article

Mutations in the major hydrophilic region (MHR) of hepatitis B virus genotype C in North China.

Journal of medical virology - 1 Dec 2012

Shi Ying, Wei Feili, Hu Dongmei, Li Qing, Smith Davey, Li Ning, Chen Dexi

Abstract excerpt

Hepatitis B virus (HBV) can evolve by mutations in the major hydrophilic region (MHR) of the HBV surface antigen (HBsAg) to permit its escape from neutralization by antibodies such as HBV surface antibody (anti-HBs) and from host immune responses. This study investigated the prevalence and pattern of MHR mutations in North China and the clinical correlations of these mutations. The MHRs of 161 HBsAg-positive...

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Share to Genes, Viral
Share to Genotyping Techniques
Share to Hepatitis B, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hydrophobic and Hydrophilic Interactions

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Source

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Identifiers

PMID: 23080494
DOI: 10.1002/jmv.23419
PMCID: PMC3747822

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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