Article
Genetic variation of putative core gene in hepatitis C virus.
Acta medica Okayama - 1 Aug 1991
Fujio K, Shimomura H, Tsuji T
Abstract excerpt
Genetic variation of hepatitis C virus was assessed. We prepared RNA fractions from 21 patients' sera which were positive for hepatitis C virus RNA, synthesized their cDNAs, and amplified fragments, 406 base pairs, encoding a putative core protein, by polymerase chain reaction. One of them, N 15, was cloned and sequenced. N 15 showed 92.4% homology at the nucleotide level and 97.0% homology at the amino acid...
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