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Article

Genetic variation of putative core gene in hepatitis C virus.

Acta medica Okayama - 1 Aug 1991

Fujio K, Shimomura H, Tsuji T

Abstract excerpt

Genetic variation of hepatitis C virus was assessed. We prepared RNA fractions from 21 patients' sera which were positive for hepatitis C virus RNA, synthesized their cDNAs, and amplified fragments, 406 base pairs, encoding a putative core protein, by polymerase chain reaction. One of them, N 15, was cloned and sequenced. N 15 showed 92.4% homology at the nucleotide level and 97.0% homology at the amino acid...

Topics

Adult
Aged
Base Sequence
Cloning, Molecular
Female
Genes, Viral
Genetic Variation
Hepacivirus
Humans
Male
Middle Aged
Molecular Sequence Data
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

RNA, Viral

Transcription, Genetic

Viral Core Proteins

Source

Identifiers

PMID: 1683739
DOI: 10.18926/AMO/32163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1683739-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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