Article
Reversible fluconazole resistance in Candida albicans: a potential in vitro model.
Antimicrobial agents and chemotherapy - 1 Mar 1997
Calvet H M, Yeaman M R, Filler S G
Abstract excerpt
To study the development and potential mechanisms of antifungal resistance in relation to antifungal exposure, reversible fluconazole resistance was examined in vitro. Candida albicans ATCC 36082 blastospores were passed in liquid yeast nitrogen base medium containing either 4, 8, 16, or 128 micrograms of fluconazole per ml, and susceptibility testing was performed after each passage. High-level fluconazole...
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