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Molecular aspects of fluconazole resistance development in <i>Candida albicans</i>

1 Sept 1999

Abstract excerpt

Serial Candida albicans isolates from recurrent episodes of oropharyngeal candidosis (OPC) in four AIDS patients which became fluconazole-resistant during therapy were analysed by molecular methods. The CARE-2 fingerprint patterns of the isolates demonstrated that in all four patients fluconazole resistance developed in a previously more susceptible strain. In two cases resistance correlated with enhanced...

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PMID: 10546486
DOI: 10.1046/j.1439-0507.1999.00498.x

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