Article
Transcriptional regulation of the mouse alpha A-crystallin gene: binding of USF to the -7/+5 region.
Gene - 7 Feb 1997
Sax C M, Cvekl A, Piatigorsky J
Abstract excerpt
Lens preferred-expression of the mouse alpha A-crystallin gene (alpha A-cry) is regulated at the transcriptional level by multiple elements located in the 5' flanking region of the gene. Here we present the first analysis of the functional role of the mouse alpha A-cry +1 region and the protein(s) which bind to it. The -7/+5 region of this promoter exhibits sequence similarity with the consensus upstream...
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