Transcriptional regulation of the mouse alpha A-crystallin gene: binding of USF to the -7/+5 region.

doi:10.1016/s0378-1119(96)00643-9

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Article

Transcriptional regulation of the mouse alpha A-crystallin gene: binding of USF to the -7/+5 region.

Gene - 7 Feb 1997

Sax C M, Cvekl A, Piatigorsky J

Abstract excerpt

Lens preferred-expression of the mouse alpha A-crystallin gene (alpha A-cry) is regulated at the transcriptional level by multiple elements located in the 5' flanking region of the gene. Here we present the first analysis of the functional role of the mouse alpha A-cry +1 region and the protein(s...

Topics

Animals
Base Sequence
Binding Sites
Binding, Competitive
Blotting, Western
Cells, Cultured
Conserved Sequence
Cricetinae
Crystallins
DNA-Binding Proteins
Humans
Lens, Crystalline
Mice
Mutation
Promoter Regions, Genetic
Rats
Recombinant Proteins
Sequence Homology, Amino Acid

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