Evidence for increased somatic cell mutations in patients with hepatocellular carcinoma.

doi:10.1093/carcin/18.2.445

Back to search

Article

Evidence for increased somatic cell mutations in patients with hepatocellular carcinoma.

Carcinogenesis - 1 Feb 1997

Okada S, Ishii H, Nose H, Okusaka T, Kyogoku A, Yoshimori M, Wakabayashi K

Abstract excerpt

The measurement of somatic cell mutation may assist in the assessment of human cancer risk. The glycophorin A (GPA) assay, which measures the frequency of variant erythrocytes in persons with blood type MN, was used to directly assess in vivo mutability in 30 patients with hepatocellular carcinom...

Topics

Carcinoma, Hepatocellular
Chromosome Deletion
Erythrocytes
Female
Flow Cytometry
Glycophorins
Hepatitis C
Humans
Liver Diseases
Liver Neoplasms
MNSs Blood-Group System
Male
Middle Aged
Mutation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.