Article
Presenilin-1 polymorphism and amyloid beta-protein deposition in fatal head injury.
Neuroreport - 20 Dec 1996
Zunarelli E, Nicoll J A, Graham D I
Abstract excerpt
Approximately 30% of patients with fatal head injuries have deposits of amyloid beta-protein (A beta); these are predominantly individuals carrying the epsilon 4 allele of apolipoprotein E (apoE). A beta deposition occurs in Alzheimer's disease (AD), for which approximately 50% of the genetic ris...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Amyloid beta-Peptides
- Apolipoproteins E
- Child
- Child, Preschool
- Craniocerebral Trauma
- Genotype
- Humans
- Immunohistochemistry
- Infant