Article
Presenilin-1 polymorphism and amyloid beta-protein deposition in fatal head injury.
Neuroreport - 20 Dec 1996
Zunarelli E, Nicoll J A, Graham D I
Abstract excerpt
Approximately 30% of patients with fatal head injuries have deposits of amyloid beta-protein (A beta); these are predominantly individuals carrying the epsilon 4 allele of apolipoprotein E (apoE). A beta deposition occurs in Alzheimer's disease (AD), for which approximately 50% of the genetic risk is attributed to apoE epsilon 4. The 1,1 genotype of a presenilin-1 (PS-1) polymorphism has been suggested to account...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.