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Article

Head injury and the risk of AD in the MIRAGE study.

Neurology - 28 Mar 2000

Guo Z, Cupples L A, Kurz A, Auerbach S H, Volicer L, Chui H, Green R C, Sadovnick A D, Duara R, DeCarli C, Johnson K, Go R C, Growdon J H, Haines J L, Kukull W A, Farrer L A

Abstract excerpt

OBJECTIVES: It has been suggested in some studies that head injury is a risk factor for AD, and that this risk is heightened among carriers of the APOE-epsilon4 allele. We examined the effects of head injury and APOE genotype on AD risk in a large family study. SUBJECTS: A total of 2,233 probands who met criteria for probable or definite AD and their 14,668 first-degree family members (4,465 parents, 7,694...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10746604
DOI: 10.1212/wnl.54.6.1316

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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