Article
Amyloid beta-protein, APOE genotype and head injury.
Annals of the New York Academy of Sciences - 17 Jan 1996
Nicoll J A, Roberts G W, Graham D I
Abstract excerpt
Deposition of amyloid beta-protein (A beta) in the brain plays a key role in the pathogenesis of Alzheimer's disease. Head injury is an epidemiological risk factor for Alzheimer's disease, and deposition of A beta occurs in approximately one third of individuals dying shortly after a severe head injury. Of the three common apolipoprotein E alleles (APOE-epsilon 2, epsilon 3, and epsilon 4) APOE-epsilon 4 allele...
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