Amyloid beta-protein, APOE genotype and head injury.

doi:10.1111/j.1749-6632.1996.tb34431.x

Back to search

Article

Amyloid beta-protein, APOE genotype and head injury.

Annals of the New York Academy of Sciences - 17 Jan 1996

Nicoll J A, Roberts G W, Graham D I

Abstract excerpt

Deposition of amyloid beta-protein (A beta) in the brain plays a key role in the pathogenesis of Alzheimer's disease. Head injury is an epidemiological risk factor for Alzheimer's disease, and deposition of A beta occurs in approximately one third of individuals dying shortly after a severe head...

Topics

Aging
Alzheimer Disease
Amyloid beta-Peptides
Apolipoprotein E4
Apolipoproteins E
Craniocerebral Trauma
Gene Frequency
Genotype
Humans
Risk Factors

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.