Article
Cerebral amyloid angiopathy in traumatic brain injury: association with apolipoprotein E genotype.
Journal of neurology, neurosurgery, and psychiatry - 1 Feb 2005
Leclercq P D, Murray L S, Smith C, Graham D I, Nicoll J A R, Gentleman S M
Abstract excerpt
OBJECTIVE: In view of the association of the apolipoprotein E (APOE) epsilon 4 allele with poor outcome after traumatic brain injury we determined the frequency of cerebral amyloid angiopathy (CAA) and the extent of haemorrhagic pathology in relation to APOE genotype in an autopsy series of 88 head injured cases. METHODS: Tissue sections from the frontal and temporal lobes were immunostained for amyloid-beta...
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