Article
Head injury and risk of Alzheimer's disease by apolipoprotein E genotype.
American journal of epidemiology - 1 Sept 1997
O'Meara E S, Kukull W A, Sheppard L, Bowen J D, McCormick W C, Teri L, Pfanschmidt M, Thompson J D, Schellenberg G D, Larson E B
Abstract excerpt
Head injury and apolipoprotein E (APOE)-epsilon 4 (e4) genotype have each been associated with increased risk of Alzheimer's disease. If APOE-e4 affects neuronal viability and branching, and if response to head injury differs in e4 patients, then the association between head injury and Alzheimer'...
Topics
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Apolipoproteins E
- Craniocerebral Trauma
- Female
- Genotype
- Humans
- Logistic Models
- Male
- Middle Aged
- Odds Ratio
- Risk
- Risk Factors
- Unconsciousness
- Washington