Article
The sparteine/debrisoquine (CYP2D6) oxidation polymorphism and the risk of lung cancer: a meta-analysis.
European journal of clinical pharmacology - 1 Jan 1997
Christensen P M, Gøtzsche P C, Brøsen K
Abstract excerpt
OBJECTIVE: To examine the association between the sparteine/debrisoquine (CYP2D6) oxidation polymorphism and the risk of lung cancer. METHOD: Meta-analysis of case-control studies using a random effects model. The "Main outcome measure" was the odds ratio for the risk of lung cancer, using extensive metabolisers as the reference group. RESULTS: Thirteen studies were identified. The studies were too heterogeneous...
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