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Rapid Degeneration of Cultured Human Brain Pericytes by Amyloid β Protein

1 Mar 1997

Abstract excerpt

Amyloid beta protein (A beta) deposition in the cerebral arterial and capillary walls is one of the major characteristics of brains from patients with Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D). Vascular A beta deposition is accompanied by degeneration of smooth muscle cells and pericytes. In this study we found that A beta 1-40 carrying the "Dutch" mutation...

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Share to Alzheimer's disease research and treatments
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PMID: 9048759
DOI: 10.1046/j.1471-4159.1997.68031135.x

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