Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect.

doi:10.1172/JCI119199

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect.

The Journal of clinical investigation - 15 Feb 1997

Lehto M, Tuomi T, Mahtani M M, Widén E, Forsblom C, Sarelin L, Gullström M, Isomaa B, Lehtovirta M, Hyrkkö A, Kanninen T, Orho M, Manley S, Turner R C, Brettin T, Kirby A, Thomas J, Duyk G, Lander E, Taskinen M R, Groop L

Abstract excerpt

Maturity-onset diabetes of the young (MODY) type 3 is a dominantly inherited form of diabetes, which is often misdiagnosed as non-insulin-dependent diabetes mellitus (NIDDM) or insulin-dependent diabetes mellitus (IDDM). Phenotypic analysis of members from four large Finnish MODY3 kindreds (linke...

Topics

Adult
Aged
Aged, 80 and over
Diabetes Mellitus, Type 2
Female
Genetic Carrier Screening
Genotype
Haplotypes
Humans
Insulin
Insulin Secretion
Lod Score
Male
Middle Aged

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pedigree

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 9045858
DOI: 10.1172/JCI119199
PMCID: PMC507838

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9045858-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.