Article
Localization of MODY3 to a 5-cM region of human chromosome 12.
Diabetes - 1 Dec 1995
Menzel S, Yamagata K, Trabb J B, Nerup J, Permutt M A, Fajans S S, Menzel R, Iwasaki N, Omori Y, Cox N J
Abstract excerpt
Maturity-onset diabetes of the young (MODY) is a heterogeneous disorder that appears to be characterized by a primary defect in insulin secretion. Mutations in an unknown locus (MODY1) on chromosome 20 and the glucokinase gene (MODY2) on chromosome 7 can cause this form of non-insulin-dependent diabetes. Recent genetic studies have identified a third locus on chromosome 12 (MODY3) that is linked to MODY in a...
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