Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Localization of MODY3 to a 5-cM region of human chromosome 12.

Diabetes - 1 Dec 1995

Menzel S, Yamagata K, Trabb J B, Nerup J, Permutt M A, Fajans S S, Menzel R, Iwasaki N, Omori Y, Cox N J

Abstract excerpt

Maturity-onset diabetes of the young (MODY) is a heterogeneous disorder that appears to be characterized by a primary defect in insulin secretion. Mutations in an unknown locus (MODY1) on chromosome 20 and the glucokinase gene (MODY2) on chromosome 7 can cause this form of non-insulin-dependent diabetes. Recent genetic studies have identified a third locus on chromosome 12 (MODY3) that is linked to MODY in a...

Topics

Adult
Chromosome Mapping
Chromosomes, Human, Pair 12
Denmark
Diabetes Mellitus, Type 2
Genetic Linkage
Germany
Humans
Japan
Mutation
Pedigree
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

United States

Source

Identifiers

PMID: 7589847
DOI: 10.2337/diab.44.12.1408

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7589847-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Localization of MODY3 to a 5-cM region of human chromosome 12.PMID 7589847Read ↗

Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q.Semantic proximity Read ↗

Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23.Semantic proximity Read ↗

Search for a third susceptibility gene for maturity-onset diabetes of the young. Studies with eleven candidate genes.Semantic proximity Read ↗

Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect.Semantic proximity Read ↗

A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.Semantic proximity Read ↗

PSMD9 is linked to MODY3.Semantic proximity Read ↗

Candidate gene studies in pedigrees with maturity-onset diabetes of the young not linked with glucokinase.Semantic proximity Read ↗

Linkage of type 2 diabetes to the glucokinase gene.Semantic proximity Read ↗

New susceptibility locus for NIDDM is localized to human chromosome 20q.Semantic proximity Read ↗

Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q.Semantic proximity Read ↗

Linkage of Genetic Markers on Human Chromosomes 20 and 12 to NIDDM in Caucasian Sib Pairs With a History of Diabetic NephropathySemantic proximity Read ↗

Linkage of serum insulin concentrations to chromosome 3p in Mexican Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.