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Article

Specific insulin and proinsulin secretion in glucokinase-deficient individuals.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Apr 1999

Pardini V C, Velho G, Reis R, Purisch S, Blanché H, Vieira J G, Moisés R C

Abstract excerpt

Glucokinase (GCK) is an enzyme that regulates insulin secretion, keeping glucose levels within a narrow range. Mutations in the glucokinase gene cause a rare form of diabetes called maturity-onset diabetes of the young (MODY). An early onset (less than 25 years), autosomal dominant inheritance and low insulin secretion stimulated by glucose characterize MODY patients. Specific insulin and proinsulin were measured...

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Source

Identifiers

PMID: 10347805
DOI: 10.1590/s0100-879x1999000400008

Genes

GCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Specific insulin and proinsulin secretion in glucokinase-deficient individuals.PMID 10347805Read ↗

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Assessment of insulin sensitivity in glucokinase-deficient subjects.Semantic proximity Read ↗

Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.Semantic proximity Read ↗

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