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Article

Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research.

Diabetes - 1 Jun 1995

Polonsky K S

Abstract excerpt

Pancreatic insulin secretion rates can be accurately derived by mathematical deconvolution of peripheral C-peptide concentrations either by using individual C-peptide kinetic parameters obtained by analysis of the decay curve of biosynthetic human C-peptide or by using published group parameters with appropriate adjustments for age and degree of obesity. Since the cross-reactivity of proinsulin and related...

Topics

Adult
Animals
Blood Glucose
C-Peptide
Chromosomes, Human, Pair 20
Diabetes Mellitus, Type 2
Genes
Glucokinase
Glucose
Humans
Insulin
Insulin Secretion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Islets of Langerhans

Mutation

Rats

Rats, Zucker

Source

Identifiers

PMID: 7789637
DOI: 10.2337/diab.44.6.705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7789637-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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