Article
Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research.
Diabetes - 1 Jun 1995
Polonsky K S
Abstract excerpt
Pancreatic insulin secretion rates can be accurately derived by mathematical deconvolution of peripheral C-peptide concentrations either by using individual C-peptide kinetic parameters obtained by analysis of the decay curve of biosynthetic human C-peptide or by using published group parameters with appropriate adjustments for age and degree of obesity. Since the cross-reactivity of proinsulin and related...
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