Article
Evidence for sex transformation of germline cells in ovarian tumor mutants of Drosophila.
Developmental biology - 1 Jan 1994
Wei G, Oliver B, Pauli D, Mahowald A P
Abstract excerpt
Mutations at a few genetic loci in Drosophila cause ovarian tumors with hundreds of poorly differentiated germ cells. We examined several of these mutants to test the hypothesis that such ovarian tumors contain sex-transformed cells. By testing for expression of male germline traits, we determined that partial germline sex transformation occurs in otu, snf, Sxlfs, and bam ovarian tumors. Thus these genes are...
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