P53 oncoprotein expression and gene mutations in some keratoacanthomas.

Article

P53 oncoprotein expression and gene mutations in some keratoacanthomas.

Archives of dermatology - 1 Feb 1997

Perez M I, Robins P, Biria S, Roco J, Siegel E, Pellicer A

Abstract excerpt

OBJECTIVE: To analyze the relationship of p53 oncoprotein overexpression in most keratoacanthomas (KAs) with gene mutations. DESIGN: Expression of p53 oncoprotein in immunohistochemical staining and its correlation to gene mutations in DNA extracted from KAs and tested in single-strand conformati...

Topics

Aged
Aged, 80 and over
DNA Mutational Analysis
Gene Expression Regulation
Humans
Keratoacanthoma
Middle Aged
Mutation
Polymorphism, Single-Stranded Conformational
Tumor Suppressor Protein p53

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