Article
Tp53/p53 status in keratoacanthomas.
Journal of cutaneous pathology - 1 Jul 2016
Joshi Sarita, Schjølberg Aasa R, Ekstrøm Per Olaf, De Angelis Paula M, Zucknick Manuela, Andersen Solveig Norheim, Clausen Ole Petter F
Abstract excerpt
BACKGROUND: Keratoacanthoma (KA) is a common keratinocytic skin neoplasm that typically develops rapidly and undergoes complete spontaneous regression. As the pro-apoptotic p53 protein may be involved in the lifecycle of KA, we studied the p53 status throughout the main stages of KA that include proliferation, maturation and regression in a large series of lesions. METHODS: One-hundred and twenty-four KAs were...
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