Article
Abundance of the longer A beta 42 in neocortical and cerebrovascular amyloid beta deposits in Swedish familial Alzheimer's disease and Down's syndrome.
Neuroreport - 31 May 1996
Kalaria R N, Cohen D L, Greenberg B D, Savage M J, Bogdanovic N E, Winblad B, Lannfelt L, Adem A
Abstract excerpt
Recent studies have demonstrated the deposition of amyloid beta (A beta) protein with carboxyl- and aminoterminal heterogeneity in cortical and cerebrovascular deposits of Alzheimer's disease (AD). Using carboxyl end-terminal specific antibodies to A beta peptides, we examined the immunocytochemi...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Amyloid beta-Peptides
- Amyloid beta-Protein Precursor
- Cerebral Cortex
- Cerebrovascular Circulation
- Down Syndrome
- Humans
- Immunohistochemistry
- Middle Aged
- Mutation
- Nerve Tissue Proteins
- Periodicity