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Article

Quantification of presenilin-1 mRNA in Alzheimer's disease brains.

FEBS letters - 7 Oct 1996

Johnston J A, Froelich S, Lannfelt L, Cowburn R F

Abstract excerpt

The presenilin-1 (PS-1) gene on chromosome 14 carries mutations which cosegregate with early-onset familial Alzheimer's disease. We quantified PS-1 mRNA in post-mortem mid-temporal and superior frontal cortices from 14 Alzheimer's disease subjects, 9 non-demented controls and 5 subjects with other neurological diseases using solution hybridisation-RNase protection assay. APP and APLP2 mRNAs had previously been...

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Source

Identifiers

PMID: 8830658
DOI: 10.1016/0014-5793(96)00969-6

Genes

APP
APLP2
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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