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Article

PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I.

Molecular and cellular biology - 1 Mar 1997

Amrani N, Minet M, Wyers F, Dufour M E, Aggerbeck L P, Lacroute F

Abstract excerpt

Cleavage and polyadenylation factor I (CF I) is one of four factors required in vitro for yeast pre-mRNA 3'-end processing. Two protein components of this factor, encoded by genes RNA14 and RNA15, have already been identified. We describe here another gene, PCF11 (for protein 1 of CF I), that genetically interacts with RNA14 and RNA15 and which presumably codes for a third protein component of CF I. This gene was...

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Identifiers

PMID: 9032237
DOI: 10.1128/MCB.17.3.1102
PMCID: PMC231835

Genes

PCF11

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I.PMID 9032237Read ↗

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RNA14 and RNA15 proteins as components of a yeast pre-mRNA 3'-end processing factor.Semantic proximity Read ↗

A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor.Semantic proximity Read ↗

An essential role for Clp1 in assembly of polyadenylation complex CF IA and Pol II transcription termination.Semantic proximity Read ↗

The interaction of Pcf11 and Clp1 is needed for mRNA 3'-end formation and is modulated by amino acids in the ATP-binding site.Semantic proximity Read ↗

The role of the yeast cleavage and polyadenylation factor subunit Ydh1p/Cft2p in pre-mRNA 3'-end formation.Semantic proximity Read ↗

Rna14p, a component of the yeast nuclear cleavage/polyadenylation factor I, is also localised in mitochondria.Semantic proximity Read ↗

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Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor.Semantic proximity Read ↗

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