Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNA14 and RNA15 proteins as components of a yeast pre-mRNA 3'-end processing factor.

Science (New York, N.Y.) - 9 Dec 1994

Minvielle-Sebastia L, Preker P J, Keller W

Abstract excerpt

Most eukaryotic pre-messenger RNAs are processed at their 3' ends by endonucleolytic cleavage and polyadenylation. In yeast, this processing requires polyadenylate [poly(A)] polymerase (PAP) and other proteins that have not yet been characterized. Here, mutations in the PAP1 gene were shown to be...

Topics

Cytochrome c Group
Cytochromes c
Fungal Proteins
Genes, Fungal
Mutation
Nuclear Proteins
Pancreatitis-Associated Proteins
Polynucleotide Adenylyltransferase
RNA Precursors
RNA Processing, Post-Transcriptional
RNA, Fungal
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA-Binding Proteins

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

mRNA Cleavage and Polyadenylation Factors

Source

Identifiers

PMID: 7992054
DOI: 10.1126/science.7992054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7992054-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNA14 and RNA15 proteins as components of a yeast pre-mRNA 3'-end processing factor.PMID 7992054Read ↗

A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor.Semantic proximity Read ↗

PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I.Semantic proximity Read ↗

Functional analysis of yeast snoRNA and snRNA 3'-end formation mediated by uncoupling of cleavage and polyadenylation.Semantic proximity Read ↗

The P-loop domain of yeast Clp1 mediates interactions between CF IA and CPF factors in pre-mRNA 3' end formation.Semantic proximity Read ↗

An essential role for Clp1 in assembly of polyadenylation complex CF IA and Pol II transcription termination.Semantic proximity Read ↗

Essential yeast protein with unexpected similarity to subunits of mammalian cleavage and polyadenylation specificity factor (CPSF).Semantic proximity Read ↗

Locked tether formation by cooperative folding of Rna14p monkeytail and Rna15p hinge domains in the yeast CF IA complex.Semantic proximity Read ↗

Pti1p and Ref2p found in association with the mRNA 3' end formation complex direct snoRNA maturation.Semantic proximity Read ↗

Effects of mutations in the Saccharomyces cerevisiae RNA14 gene on the abundance and polyadenylation of its transcripts.Semantic proximity Read ↗

Coupling of termination, 3' processing, and mRNA export.Semantic proximity Read ↗

Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase.Semantic proximity Read ↗

Rna14p, a component of the yeast nuclear cleavage/polyadenylation factor I, is also localised in mitochondria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.