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Article

RNA14 and RNA15 proteins as components of a yeast pre-mRNA 3'-end processing factor.

Science (New York, N.Y.) - 9 Dec 1994

Minvielle-Sebastia L, Preker P J, Keller W

Abstract excerpt

Most eukaryotic pre-messenger RNAs are processed at their 3' ends by endonucleolytic cleavage and polyadenylation. In yeast, this processing requires polyadenylate [poly(A)] polymerase (PAP) and other proteins that have not yet been characterized. Here, mutations in the PAP1 gene were shown to be synergistically lethal with previously identified mutations in the RNA14 and RNA15 genes, which suggests that their...

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Source

Identifiers

PMID: 7992054
DOI: 10.1126/science.7992054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RNA14 and RNA15 proteins as components of a yeast pre-mRNA 3'-end processing factor.PMID 7992054Read ↗

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An essential role for Clp1 in assembly of polyadenylation complex CF IA and Pol II transcription termination.Semantic proximity Read ↗

Essential yeast protein with unexpected similarity to subunits of mammalian cleavage and polyadenylation specificity factor (CPSF).Semantic proximity Read ↗

Locked tether formation by cooperative folding of Rna14p monkeytail and Rna15p hinge domains in the yeast CF IA complex.Semantic proximity Read ↗

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Effects of mutations in the Saccharomyces cerevisiae RNA14 gene on the abundance and polyadenylation of its transcripts.Semantic proximity Read ↗

Coupling of termination, 3' processing, and mRNA export.Semantic proximity Read ↗

Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase.Semantic proximity Read ↗

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