Article
Prevalence and clinical correlates of somatic mutation in aldosterone producing adenoma-Taiwanese population.
Scientific reports - 12 Jun 2015
Wu Vin-Cent, Huang Kuo-How, Peng Kang-Yung, Tsai Yao-Chou, Wu Che-Hsiung, Wang Shuo-Meng, Yang Shao-Yu, Lin Lian-Yu, Chang Chin-Chen, Lin Yen-Hung, Lin Shuei-Liong, Chu Tzong-Shinn, Wu Kwan-Dun
Abstract excerpt
Primary aldosteronism (PA) is a common form of secondary hypertension and has significant cardiovascular consequences. Mutated channelopathy due to the activation of calcium channels has been recently described in aldosterone-producing adenoma (APA). The study involved 148 consecutive PA patients, (66 males; aged 56.3 ± 12.3years) who received adrenalectomy, and were collected from the Taiwan PA investigator...
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