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Article

G protein and thyrotropin receptor mutations in thyroid neoplasia.

The Journal of clinical endocrinology and metabolism - 1 Feb 1997

Esapa C, Foster S, Johnson S, Jameson J L, Kendall-Taylor P, Harris P E

Abstract excerpt

The cAMP pathway plays a central role in thyroid follicular cell growth and function. Mutations of the TSH receptor (TSHR) or G proteins (gsp) that activate adenylyl cyclase have been identified in autonomously functioning thyroid nodules. Gsp mutations have been identified also in other forms of thyroid neoplasia, but their reported prevalence has been extremely variable. We have studied the prevalence of gsp...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9024242
DOI: 10.1210/jcem.82.2.3719

Genes

TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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G protein and thyrotropin receptor mutations in thyroid neoplasia.PMID 9024242Read ↗

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