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Article

Somatic mutations in thyroid nodular disease.

Molecular genetics and metabolism - 1 Mar 2002

Krohn Knut, Paschke Ralf

Abstract excerpt

Thyroid nodules can be found in up to 50% of inhabitants of iodine-deficient areas and are classified as hot or cold thyroid nodules according to their scintigraphic characteristics. Studies of hot thyroid nodules with comparable mutation detection methods and screening at least exon 10 of the TSH receptor reported frequencies for somatic TSH-receptor mutations ranging from 20 to 82% in patients with similar...

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PMID: 11914031
DOI: 10.1006/mgme.2001.3290

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