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Article

P53 gene mutations in osteosarcomas in the dog.

Cancer letters - 1 Jan 1997

van Leeuwen I S, Cornelisse C J, Misdorp W, Goedegebuure S A, Kirpensteijn J, Rutteman G R

Abstract excerpt

Osteosarcomas in 18 dogs were examined for the presence of p53 mutations in exons 4-8 by single strand conformation polymorphism (SSCP) analysis, followed by sequence analysis in tumors demonstrating abnormal bands in the SSCP analysis. P53 mutations were found in four of the primary tumors in 17 dogs. Metastases studied in two of these dogs in which the primary tumor contained only wild type p53 did not contain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9022143
DOI: 10.1016/s0304-3835(96)04529-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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