P53 mutations in mammary tumor cell lines and corresponding tumor tissues in the dog.

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Article

P53 mutations in mammary tumor cell lines and corresponding tumor tissues in the dog.

Anticancer research - 1 Jan 2000

Van Leeuwen I S, Hellmèn E, Cornelisse C J, Van den Burgh B, Rutteman G R

Abstract excerpt

Alterations in the p53 gene are frequently observed in a wide variety of human cancers. To elucidate the role of p53 in tumorigenesis of the dog, we analyzed nine mammary tumor cell lines, and the primary or metastatic tumors used for their establishment, for the presence of genomic p53 abnormali...

Topics

Amino Acid Sequence
Animals
Base Sequence
Blotting, Southern
DNA Mutational Analysis
Dog Diseases
Dogs
Female
Genes, p53
Mammary Neoplasms, Animal
Molecular Sequence Data
Mutation
Polymorphism, Single-Stranded Conformational
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 9042250

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9042250-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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