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Article

The Search for 'Evolution-Proof' Antibiotics.

Trends in microbiology - 1 Jun 2018

Bell Graham, MacLean Craig

Abstract excerpt

The effectiveness of antibiotics has been widely compromised by the evolution of resistance among pathogenic bacteria. It would be restored by the development of antibiotics to which bacteria cannot evolve resistance. We first discuss two kinds of 'evolution-proof' antibiotic. The first comprises literally evolution-proof antibiotics to which bacteria cannot become resistant by mutation or horizontal gene...

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Identifiers

PMID: 29191398
DOI: 10.1016/j.tim.2017.11.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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