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Identification of polymorphisms in the p53 gene by denaturing gradient gel blots.

Human heredity - 1 Jan 2000

Nogueira C P

Abstract excerpt

Polymorphisms in the tumor suppressor gene p53 were identified by Southern blots of denaturing gradient gels (melting polymorphisms). Five polymorphisms were identified in white blood cell DNA, with the frequency of heterozygotes varying from 4 to 27%. The strategy of hybridizing the same blots with different probes suggests that two of the polymorphisms are located in the region of exons 5-6 and one is in the...

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PMID: 9017981
DOI: 10.1159/000154390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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