Transient expression of M-CSF is important for osteoclast-like cell differentiation in a monocytic leukemia cell line.

doi:10.1002/(sici)1097-4644(199701)64:1<67::aid-jcb10>3.0.co;2-h

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Article

Transient expression of M-CSF is important for osteoclast-like cell differentiation in a monocytic leukemia cell line.

Journal of cellular biochemistry - 1 Jan 1997

Aoki H, Akiyama H, Hosoya H, Souda M, Morioku T, Marunouchi T

Abstract excerpt

Cells of U937, a human monocytic leukemia cell line, differentiate into macrophages by treatment with 12-o-tetradecanoylphorbol-13-acetate (TPA), whereas cells treated with 1 alpha, 25-dihydroxyvitamin D3 [1,25-(OH)2D3] continue to grow without undergoing differentiation. When U937 cells were suc...

Topics

Acid Phosphatase
Animals
Calcitonin
Calcitriol
Carcinogens
Cell Differentiation
Cell Nucleus
Dexamethasone
Diterpenes
Drug Synergism
Gene Expression Regulation, Leukemic
Genes, fms
Genes, src
Humans
Interferon-gamma
Isoenzymes
Leukemia, Monocytic, Acute
Macrophage Colony-Stimulating Factor

Source

Open in PubMed

Identifiers

PMID: 9015756
DOI: 10.1002/(sici)1097-4644(199701)64:1<67::aid-jcb10>3.0.co;2-h

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9015756-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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