Article
Gamma interferon augments functional and phenotypic characteristics of vitamin D3-induced monocytoid differentiation in the U937 human leukaemic cell line.
Leukemia research - 1 Jan 1990
Kelsey S M, Makin H L, Macey M G, Newland A C
Abstract excerpt
We studied the effect of gamma interferon on 1,25-dihydroxyvitamin D3 (1,25(OH)2D3)-induced differentiation of the human leukaemic cell line U937. Both phenotypic and functional aspects of 1,25(OH)2D3-induced differentiation were significantly augmented by gamma interferon (IFN). Gamma interferon...
Topics
- Antigens, Differentiation, Myelomonocytic
- Calcitriol
- Cell Differentiation
- Cell Division
- Drug Synergism
- Humans
- Interferon-gamma
- Leukemia
- Lipopolysaccharide Receptors
- Monocytes
- Phagocytosis
- Phenotype
- Receptors, Fc
- Superoxides
- Tumor Cells, Cultured