Article
Gene expression during osteoclast-like cell formation induced by antifusion regulatory protein-1/CD98/4F2 monoclonal antibodies (MAbs): c-src is selectively induced by anti-FRP-1 MAb.
Bone - 1 Jul 1999
Higuchi Y, Ito M, Tajima M, Higuchi S, Miyamoto N, Nishio M, Kawano M, Kusagawa S, Tsurudome M, Sudo A, Katou K, Uchida A, Ito Y
Abstract excerpt
Human blood monocytes can differentiate into osteoclast-like cells when they are cultured in the presence of anti-FRP-1. Messenger (mRNA) expression of markers related to osteoclasts was analyzed during differentiation of osteoclasts from monocytes. As markers related to osteoclasts, we selected cathepsin-K, carbonic anhydrase (CA) II, vacuolar H(+)-ATPase (v-ATPase), vitronectin receptor (VNR),...
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