Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Characterization of mice deficient in interleukin-1 beta converting enzyme.

Journal of cellular biochemistry - 1 Jan 1997

Li P, Allen H, Banerjee S, Seshadri T

Abstract excerpt

Interleukin-1 beta converting enzyme (ICE) processes the inactive prolL-1 beta to the proinflammatory mature IL-1 beta. ICE belongs to a family of cysteine proteases that have been implicated in apoptosis. To address the biological functions of ICE, we generated ICE-deficient mice through gene ta...

Topics

Join the communities discussing this publication.

Mice
Heterozygote
Mice, Inbred C57BL
Age Factors
Apoptosis
Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Adenosine Triphosphate

Source

Identifiers

PMID: 9015751
DOI: 10.1002/(sici)1097-4644(199701)64:1<27::aid-jcb5>3.0.co;2-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9015751-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of mice deficient in interleukin-1 beta converting enzyme.PMID 9015751Read ↗

Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-α-Mediated Inflammation In Vivo.Semantic proximity Read ↗

Gene targeting technology and advances in the pathophysiology of inflammation.Semantic proximity Read ↗

Structure and mechanism of interleukin-1 beta converting enzyme.Semantic proximity Read ↗

Interleukin-10 gene knock-out mice: a model of chronic inflammation.Semantic proximity Read ↗

Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection.Semantic proximity Read ↗

Caspase-1 self-terminates protease activity to enforce homeostasis and prevent inflammasome-driven diseasesSemantic proximity Read ↗

Exploring caspase functions in mouse modelsSemantic proximity Read ↗

Phenotypic and functional characterization of mice that lack the type I receptor for IL-1.Semantic proximity Read ↗

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.Semantic proximity Read ↗

Generation of mice with a conditional allele for transforming growth factor beta 1 gene.Semantic proximity Read ↗

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice.Semantic proximity Read ↗

Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.