Article
Polymorphisms of the TAP1 and TAP2 transporter genes in Japanese SLE.
Annals of the rheumatic diseases - 1 Dec 1996
Takeuchi F, Nakano K, Nabeta H, Hong G H, Kuwata S, Ito K
Abstract excerpt
OBJECTIVE: To determine how polymorphism of transporter associated with antigen processing 1 and 2 (TAP1 and 2) alleles contributed to the pathogenesis of systemic lupus erythematosus (SLE) in Japanese patients. METHODS: TAP1 and TAP2 typing was carried out in 52 Japanese patients with SLE and 95 normal subjects by the PCR-RFLP (restriction fragment length polymorphism) method. HLA-DR typing and HLA-DRB1*15...
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