Article
TAP1 and TAP2 gene polymorphism in rheumatoid arthritis in a population in eastern France.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Jun 2002
Zhang S-L, Chabod J, Penfornis A, Reviron D, Tiberghien P, Wendling D, Toussirot E
Abstract excerpt
The 'transporter associated with antigen processing' (TAP) gene products are involved in the processing of endogenous peptides that bind to class I molecules. Polymorphism within these genes could alter the level of the immune response, a phenomenon relevant to the development of autoimmune diseases. In this study, we examined the polymorphism of TAP1 and TAP2 genes in patients with rheumatoid arthritis (RA)....
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