Article
Correlations and Influence of TAP2 Genes Polymorphisms and Systemic Lupus Erythematosus Propensity.
Current rheumatology reviews - 1 Jan 2021
Rezaieyazdi Zahra, Nomani Hosein, Hatef Mohammad Reza, Afshari Jalil Tavakol, Abbasi Mahnaz, Esmaily Habibollah, Khodashahi Mandana
Abstract excerpt
OBJECTIVES: The present study was designed to evaluate the association of transporters associated with antigen processing (TAP2) polymorphisms TAP2-379Ile > Val (rs1800454), TAP2-665Thr > Ala (rs241447) and TAP2-565Ala > Thr (rs2228396) as a candidate gene with susceptibility to the Systemic Lupus Erythematosus (SLE). METHODS: To analyze these three polymorphic variants, 88 patients with SLE and 100 healthy...
Read the complete abstract on PubMed