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Article

Genetic polymorphisms of the major histocompatibility complex-encoded antigen-processing genes TAP and LMP in sarcoidosis.

Human immunology - 1 Feb 1996

Ishihara M, Ohno S, Mizuki N, Yamagata N, Ishida T, Naruse T, Kuwata S, Inoko H

Abstract excerpt

Sarcoidosis is a granulomatous disease showing a significant increase in the HLA-DR5, -DR6, and -DR8 associated alleles in Japanese. To investigate whether the class I antigen-processing genes, encoded within the MHC class II region between the HLA-DP and -DQ loci, are involved in determining the susceptibility to sarcoidosis, TAP1, TAP2, and LMP2 alleles were analyzed by the PCR-RFLP method in 85 Japanese...

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Source

Identifiers

PMID: 8882407
DOI: 10.1016/0198-8859(95)00167-0

Genes

TAP1
TAP2

Provenance

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