Article
Association of TAP1 and TAP2 with systemic sclerosis in Japanese.
Clinical and experimental rheumatology - 1 Jan 2000
Takeuchi F, Kuwata S, Nakano K, Nabeta H, Hong G H, Shibata Y, Tanimoto K, Ito K
Abstract excerpt
OBJECTIVE: The contribution of polymorphism of transporter associated with antigen processing 1 and 2 (TAP1 and 2) alleles to the pathogenesis of Japanese SSc was studied. METHODS: TAP1 and TAP2 typing was carried out in 55 Japanese SSc patients and 95 normal Japanese subjects by the PCR-RFLP (restriction fragment length polymorphism) method. HLA-DR typing and HLA DRB1*15, *16 and *08 genotyping were carried out...
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