An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter.

doi:10.1210/mend.11.2.9883

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Article

An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter.

Molecular endocrinology (Baltimore, Md.) - 1 Feb 1997

Cleutjens K B, van der Korput H A, van Eekelen C C, van Rooij H C, Faber P W, Trapman J

Abstract excerpt

Prostate-specific antigen (PSA) is expressed at a high level in the luminal epithelial cells of the prostate and is absent or expressed at very low levels in other tissues. PSA expression can be regulated by androgens. Previously, two functional androgen-response elements were identified in the p...

Topics

Androgens
Animals
Base Sequence
Binding Sites
Cells, Cultured
Chromatin
Chromosome Mapping
Deoxyribonuclease I
Dihydrotestosterone
Enhancer Elements, Genetic
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Metribolone

Molecular Sequence Data

Mutation

Organ Specificity

Promegestone

Promoter Regions, Genetic

Source

Open in PubMed

Identifiers

PMID: 9013762
DOI: 10.1210/mend.11.2.9883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9013762-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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